Abstract: Based on the P-phase arrival time, we determined the source location of the Jishishan M6.2 earthquake with simulated annealing (SA) method, and quantitatively evaluated the reliability of the results using sample set statistical analysis method. The results show that the source location of the Jishishan M6.2 earthquake is (35.750°N, 102.833°E), at a depth of 12.0 km. At a 95% confidence level, the confidence interval for the parameter solution of the source location is (35.748°N～35.753°N, 102.830°E～102.836°E), at a depth of 6.8～16.9 km.