Abstract: Based on observation data of the water level and water temperature in the Dehongfapa well from 2008 to 2023, we analyzed the characteristics of the dynamic change of observation data, pattern of earth tides, coseismic response, and earthquake precursor anomaly. The results showed that the water level of the Dehongfapa well has a clear pattern of earth tides and that the annual variation is obvious highness of level in summer and lowness in winter. The annual variation of water temperature was less than 0.01℃, indicating a stable trend type. The coseismic response of the well water level and water temperature was obvious. The coseismic response ratio of M_S≥6.0 earthquakes in the study area was 78.6%. The well water level and water temperature can record some obvious precursor anomalies, mainly characterized by short-term anomalies in time and proximal and local earthquakes in space. We systematically studied, cleaned, and analyzed the fluid observation data of the Dehongfapa well and found that the aquifer of the Dehongfapa well has good elasticity. The observation data of the well can effectively reflect the underground stress and strain change, so the Dehongfapa well is an ideal fluid observation well. It can provide information useful for earthquake prediction.