Abstract: The probability of earthquake occurring in rural areas is greater than that in urban areas, and rural residents’ awareness of earthquake prevention and disaster reduction is relatively low. Affected by subjective and objective factors, rural areas are prone to property losses and casualties due to earthquake disasters. Based on the sample survey of Midu County, Dali Prefecture, Yunnan Province, this paper analyzes the rural residents’ demand for earthquake prevention and disaster reduction publicity and their willingness to participate in the popularization of earthquake prevention and disaster reduction as the main body, and explores the ways and approaches for the rural residents to participate in the popularization of earthquake prevention and disaster reduction. The analysis shows that under the continuous efforts of traditional media and emerging media, most villagers have been exposed to earthquake knowledge, and they prefer various forms, strong practicability, local characteristics, simple, quick and easy to understand the publicity methods of acquiring knowledge. However, due to the influence of activity information transmission, villagers’ education level, occupation, ability, interest, time and other factors, villagers are not willing to participate in the popularization of earthquake prevention and disaster reduction, and the simple way of implementation and strong incentive method are relatively popular. By increasing the benefits of participation, reducing the cost of participation, and facilitating the flow of information, the participation of all rural residents in the popularization of earthquake preparedness and disaster reduction can be gradually realized.