Abstract: The DSQ water pipe inclinometer, as a deformation instrument for observing physical quantities of crustal deformation, plays an important role in earthquake analysis and prediction by extracting non tidal signals and identifying transient events to capture micro dynamic information of crustal deformation during earthquake preparation. In order to ensure the authenticity and reliability of the instrument observation data, the DSQ water pipe inclinometer needs to be calibrated regularly to ensure the stability of its grid parameters. In the traditional calibration method, there are many processes for adjusting electrical sensitivity, which often require multiple adjustments to succeed. This not only makes it cumbersome, time-consuming, and inefficient, but also seriously affects the continuity and completeness of data. Through years of summarizing and exploring the actual operation of the water pipe inclinometer calibration process, a fast calibration and debugging method has been discovered and promoted for verification at multiple stations. It can quickly and efficiently complete the calibration work, which is of great significance for producing stable, complete, and reliable observation data.