Abstract: The eastern margin of the Tibetan Plateau is a tectonic transformation belt regulating the eastward extrusion of materials from the plateau. This area not only has high density active faults and high frequency strong earthquakes, but also has very complex geological and geomorphological features. So it is one of the most serious earthquake hazard areas in China. In recent years, with the development of seismic hazard risk survey and active fault detection, the investigation and study on the strong earthquakes, seismogenic structures and related earthquake hazards in the eastern margin of the Qinghai-Tibet Plateau and adjacent areas have been continuously improved. In order to timely exchange relevant research results and support regional earthquake prevention and hazard reduction and geological safety evaluation, the journal editorial department of Progress in Earthquake Sciences organized two special topics of “The strong earthquakes and seismogenic structures in eastern margin of Tibetan Plateau and adjacent areas”. In this special topic, a total of 11 representative articles in the fields of strong earthquake structures, earthquake and hazard and tectonic geomorphology were collected and selected. We hope that these new research results may further improve the understanding on regional strong earthquake structural characteristics, seismic hazard and the law of triggering geological hazards, so as to provide scientific basis or reference for preventing the risk of strong earthquake hazards.