Abstract: This paper summed up the interference factors of Quanzhou seismic station g-phone gravimeter observation data. It is considered that the change of working state and the influence of meteorological factors are the main interference factors. The change of the internal temperature of the instrument has a great influence on the data, so it is necessary to avoid the change of the internal temperature caused by manual operation such as power failure. The rainfall and the change of air pressure caused by typhoons increased the noise of the data.